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Cohort study, 2009

Does ovulation affect mood changes during the menstrual cycle in healthy women?

Healthy women showed small mood changes across their cycle regardless of whether they ovulated, though women who did not ovulate had more variable but less negative mood overall. Mood changes did not depend on how long the luteal phase was.

Moderate study design 62 healthy women initially ovulatory, mean age 33.9 years

What they did

62 healthy women initially ovulating tracked ovulation, exercise, and mood daily for one year. Basal body temperature was used to determine the start of the luteal phase. Women rated feeling depressed, anxious, and angry or frustrated on a scale from 0 (absent) to 4 (very intense).

What they found

Of 739 cycles classified: 532 (72%) were normally ovulatory, 185 (25%) were ovulatory with a short luteal phase (less than 10 days), and 22 (3%) were anovulatory. Minor cyclic mood changes were present in both ovulatory and anovulatory cycles. In anovulatory cycles, mood tended to be more variable but less negative, with a time course that differed from ovulatory cycles. Mood scores did not differ based on luteal phase length or hormone levels.

What it means for you

Even without ovulation, mood still changes across the cycle, but the pattern is somewhat different. This suggests factors beyond ovulation and hormones influence mood cyclicity. In women with very severe PMS, patterns appear to be amplifications of normal experiences. The study is observational from one research group.

765

menstrual cycles tracked across the year

72%

normally ovulatory cycles

25%

ovulatory cycles with short luteal phase

About the study

Original title
Ovulation disturbances and mood across the menstrual cycles of healthy women
Authors
Harvey AT, Hitchcock CL, Prior JC
Journal
Journal of psychosomatic obstetrics and gynaecology
Year
2009
Study design
Cohort study
Participants
62
What was tested
None (observational tracking)

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