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Review, 1993

What are the medication options for treating PMS?

PMS can be treated with hormonal medications that alter the menstrual cycle, mood drugs, diuretics for fluid retention, and pain relievers for headaches. Treatment should start with simpler measures and consider side effects.

Moderate study design Literature review (not a study of specific individuals)

What they did

Literature review of PMS diagnosis and pharmacological management, examining different medication strategies and treatment approaches.

What they found

Treatment options include hormonal medications (transdermal estrogen, cyclic oral progesterone, oral contraceptives, danazol, GnRH agonists), psychotropic medications (fluoxetine, clomipramine, alprazolam), diuretics for fluid retention, bromocriptine or tamoxifen for breast pain, and pain relievers for headaches. Two approaches exist: symptom-oriented management or modification of the menstrual cycle.

What it means for you

Multiple effective treatments exist for PMS but the choice depends on which symptoms are most bothersome and which side effects a woman can tolerate. Medication should only be started after simpler measures have failed.

2

Treatment approaches: symptom-oriented or cycle modification

About the study

Original title
Pharmacologic strategies for managing premenstrual syndrome
Authors
Moline ML
Journal
Clinical pharmacy
Year
1993
Study design
Review
What was tested
Various medications including hormonal treatments, psychotropic drugs, diuretics, and pain relievers

Topics