Study, 1977
Do brain chemicals that affect mood change during the menstrual cycle in women with PMS?
In 12 women with PMS, the enzymes that break down these brain chemicals did not show clear changes across the cycle, unlike what was found in women without PMS.
Early or limited evidence 12 women with PMS
What they did
Measured two specific enzymes in 12 women with PMS throughout their menstrual cycle.
What they found
There was no clear variation of the measured enzymes during the menstrual cycle in women with PMS. Previous studies found these enzyme levels declined before menstruation in women without PMS and in monkeys, but this study did not find that pattern.
What it means for you
This suggests women with PMS might have a different enzyme pattern than women without PMS, which could help explain their symptoms. However, the study only included 12 women, so the findings may not apply to all women.
12
Women with PMS studied
About the study
- Original title
- Platelet monoamine oxidase in women with premenstrual syndrome
- Authors
- Feine R, Belmaker RH, Rimon R et al.
- Journal
- Neuropsychobiology
- Year
- 1977
- Study design
- Study
- Participants
- 12
- What was tested
- None
- Read the paper
- doi.org/10.1159/000117594