Skip to content

Review, 2018

What are the most effective treatments for premenstrual syndrome and PMDD?

Serotonin reuptake inhibitors and contraceptives with shortened or no hormone-free interval are the most effective treatments. Some women who do not respond may benefit from GnRH agonist treatment.

Strong study design Women with premenstrual disorders (review article)

What they did

Researchers reviewed scientific evidence on treatments for premenstrual disorders including PMS, PMDD, and premenstrual worsening of other medical conditions.

What they found

Serotonin reuptake inhibitors and contraceptives with shortened to no hormone-free interval are the most efficacious treatments for PMS and PMDD. Women who do not respond to these and other interventions may benefit from gonadotropin-releasing hormone agonist treatment.

What it means for you

These treatments have the most evidence showing they work. The underlying causes are still being studied, and individual response varies between women.

About the study

Original title
Premenstrual disorders
Authors
Yonkers KA, Simoni MK
Journal
American journal of obstetrics and gynecology
Year
2018
Study design
Review
What was tested
Not applicable (review of treatments)

Topics