Review, 2024
What are the most effective treatments for PMDD?
According to this literature review, SSRIs (antidepressants) and cognitive-behavioral therapy are the most commonly recommended first-line treatments. Birth control pills with drospirenone are also effective.
What they did
Literature review of 32 articles published between June and July 2021 from databases including PubMed, Scopus, and Cochrane. Researchers searched for information on drug and psychotherapy treatments for PMDD and their effectiveness.
What they found
SSRIs are first-line treatment with these dose ranges: sertraline 50-150 mg per day, fluoxetine 10-20 mg per day, escitalopram 10-20 mg per day, paroxetine 12.5-25 mg per day. Birth control pills with drospirenone are first or second line treatments. Cognitive behavioral therapy showed positive results in reducing the functional impact of PMDD.
What it means for you
Women with PMDD have several evidence-based treatment options including medications and therapy. SSRIs are the primary drug choice recommended. This review synthesizes existing research but only searched literature through July 2021, so recent studies may be missed.
32
articles reviewed
50-150 mg/day
sertraline dose range
10-20 mg/day
fluoxetine dose range
About the study
- Original title
- [Premenstrual dysphoric disorder (PMDD): Drug and psychotherapeutique management, a literature review]
- Authors
- Marais-Thomas H, Chapelle F, de Vaux-Boitouzet V et al.
- Journal
- L'Encephale
- Year
- 2024
- Study design
- Review
- What was tested
- SSRIs, drospirenone birth control, and cognitive behavioral therapy
- Read the paper
- doi.org/10.1016/j.encep.2023.08.007
Topics
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