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Randomised trial, 1990

What is PMS and how should doctors diagnose it?

PMS is a disorder with symptoms only during the luteal phase, with at least one week each cycle completely symptom-free. Symptoms must interfere significantly with normal life. Up to 50% of people who think they have PMS actually have depression instead.

Moderate study design General literature review; no specific participants

What they did

This clinical review describes how to diagnose PMS and summarizes available treatments based on double-blind placebo-controlled studies.

What they found

PMS diagnosis requires prospective symptom tracking showing symptoms only in the luteal phase and at least one symptom-free week in the follicular phase. Symptoms must be severe enough to disrupt normal function. Most patients with suspected PMS actually have a depressive disorder. Laboratory tests are not helpful for diagnosis. Treatment varies by symptom type.

What it means for you

The key takeaway is that many people are misdiagnosed. Proper diagnosis requires careful tracking. This is a summary of existing knowledge rather than a new study.

50

Percentage of suspected PMS patients who actually have depression

1

Minimum weeks symptom-free in follicular phase for PMS diagnosis

About the study

Original title
Premenstrual syndrome: an update for the clinician
Authors
Chihal HJ
Journal
Obstetrics and gynecology clinics of North America
Year
1990
Study design
Randomised trial
Participants
50

Topics