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Randomised trial, 2000

How should PMS and PMDD be managed?

SSRIs are the most effective treatment for PMDD and can be taken daily or just during the premenstrual week, with excellent results and minimal side effects.

Strong study design Women with PMS and PMDD (guideline update)

What they did

Clinical guidelines and expert update on managing PMS and PMDD based on research evidence.

What they found

PMDD affects 3 to 8% of women, compared to 75% with some PMS symptoms. SSRIs have excellent efficacy and minimal side effects in randomized trials. Intermittent SSRIs (taken only premenstrually) are equally effective as daily dosing.

What it means for you

SSRIs are the best current treatment for PMDD and can be used flexibly. Women can work with their doctor to find what works best. Guidelines can become outdated as new research emerges.

3% to 8%

Women with PMDD

75%

Women with some PMS symptoms

About the study

Original title
Premenstrual syndrome and premenstrual dysphoric disorder: guidelines for management
Authors
Steiner M
Journal
Journal of psychiatry & neuroscience : JPN
Year
2000
Study design
Randomised trial
What was tested
SSRIs (daily or intermittent), lifestyle and stress management
Open access
Yes

Topics