Randomised trial, 1997
What treatments are proven to work for PMS?
Recent trials show serotonergic antidepressants and gonadotropin-releasing hormone agonists effectively treat PMS. Preliminary evidence supports spironolactone and carbohydrate-rich beverages.
What they did
This is a literature review article that summarizes recent randomized controlled trials testing PMS treatments and discusses neuroendocrine research findings.
What they found
Randomized trials showed that serotonergic antidepressants and gonadotropin-releasing hormone agonist are effective treatments. Preliminary data suggested benefit from spironolactone and carbohydrate-rich beverages. Multiple neuroendocrine studies reported findings suggesting an underlying neurobiological vulnerability in PMS.
What it means for you
Multiple treatment approaches have been tested in recent research. Some are well-proven (antidepressants, hormone therapy) while others show only preliminary promise. This review was published in 1997 and newer treatments may now be available.
About the study
- Original title
- Premenstrual syndrome: current perspectives on treatment and etiology
- Authors
- Freeman EW
- Journal
- Current opinion in obstetrics & gynecology
- Year
- 1997
- Study design
- Randomised trial
- What was tested
- Antidepressants, hormone agonist, spironolactone, carbohydrate-rich beverages
- Read the paper
- https://pubmed.ncbi.nlm.nih.gov/9263696/
Topics
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