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Cohort study, 2005

Is PMDD a strong risk factor for postpartum depression?

Yes, women with PMDD have a 9.3-fold higher risk of major postpartum depression than women without PMDD.

Moderate study design 1800 postpartum women (133 at high risk, 109 at low risk)

What they did

A prospective study of 1800 postpartum women. They were assessed for risk factors 2-4 days after giving birth, then called back at 6-8 weeks to ask about mood changes.

What they found

PMDD was the strongest risk factor found. Compared to women at low risk, women at high risk had a 9.3-fold increase in major depression, 1.5-fold increase in minor depression, 1.6-fold increase in postpartum blues, and 2.6-fold increase in adjustment disorder.

What it means for you

Women with PMDD may be at much higher risk for mood problems after pregnancy and may need extra support or monitoring. However, the study asked women to remember past PMDD symptoms rather than measuring them directly, which could be less accurate.

1800

postpartum women

9.3

fold increase in major depression risk with PMDD

6-8 weeks

time of follow-up assessment after delivery

About the study

Original title
Risk factors associated with the development of postpartum mood disorders
Authors
Bloch M, Rotenberg N, Koren D et al.
Journal
Journal of affective disorders
Year
2005
Study design
Cohort study
Participants
1,800
What was tested
None (observational study)

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