Systematic review, 2021
Does PMDD increase the risk of suicidality?
Yes. Women with PMDD have significantly higher risk of suicidal thoughts (2.34 times higher), suicide attempts (2.13 times higher), and suicide plans (2.24 times higher).
What they did
They searched 4 electronic databases up to November 2020, found 6 studies with 8,532 participants total, and combined the results using meta-analysis.
What they found
Women with PMDD had 2.34 times higher risk of suicidal ideation, 2.13 times higher risk of suicide attempt, and 2.24 times higher risk of suicidal plan. These findings were consistent across studies.
What it means for you
Women with PMDD should be monitored for signs of suicidal thoughts and behavior. The main limitation is that PMDD diagnosis was provisional in all included studies, not confirmed with full diagnostic criteria.
8,532
total participants across all studies
2.34
times higher risk of suicidal ideation
2.13
times higher risk of suicide attempt
About the study
- Original title
- Suicidality in patients with premenstrual dysphoric disorder-A systematic review and meta-analysis
- Authors
- Yan H, Ding Y, Guo W
- Journal
- Journal of affective disorders
- Year
- 2021
- Study design
- Systematic review
- What was tested
- N/A - observational study
- Read the paper
- doi.org/10.1016/j.jad.2021.08.082
Topics
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