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Survey study, 2008

Does low progesterone cause PMS?

No. Research by Professor Dennerstein showed that low progesterone does not cause PMS, even though hormones affect mood and behavior across the menstrual cycle.

Early or limited evidence Review of research on women across reproductive years

What they did

Review of published research on how reproductive hormones relate to behavior across the menstrual cycle.

What they found

Studies by Professor Dennerstein showed that hormones affect psychological symptoms and behavior across the menstrual cycle. Her research definitively refuted the theory that low progesterone causes PMS. Sexual behavior shows a cyclic pattern but does not clearly relate to measured hormone levels.

What it means for you

Although hormones change across the menstrual cycle, low progesterone alone does not explain PMS. The relationship between hormones and mood is complex. This is a review summarizing past research, not new findings.

About the study

Original title
The endocrinology of the reproductive years
Authors
Randolph JF Jr
Journal
The journal of sexual medicine
Year
2008
Study design
Survey study
What was tested
None, review article
Open access
Yes

Topics