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Survey study, 2001

Do antidepressants work for PMDD?

Yes, according to this review. Serotonergic antidepressants have shown effectiveness for premenstrual dysphoric disorder, whether taken every day or just during the luteal phase before the period.

Early or limited evidence Women across the lifespan, with focus on reproductive years

What they did

A review article discussing depression in women at different life stages, including how antidepressants work and how to use them safely during pregnancy and at different ages.

What they found

Depression is more common in women than men, especially during reproductive years. Depression can occur during the premenstrual period, pregnancy, postpartum, and perimenopause. For PMDD, serotonergic agents have demonstrated efficacy in both full-cycle and luteal-phase dosing strategies. Limited safety data suggest antidepressants pose minimal danger to fetuses or infants.

What it means for you

Antidepressants appear to help PMDD, and doctors can choose to give them continuously or just during the luteal phase before your period. This is a review article summarizing other people's research rather than new research itself.

About the study

Original title
The evaluation and management of depression in women across the life span
Authors
Kornstein SG
Journal
The Journal of clinical psychiatry
Year
2001
Study design
Survey study
What was tested
Serotonergic antidepressant medications

Topics