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Study, 1942

What causes premenstrual tension and can progesterone help?

The paper reviews existing theories suggesting premenstrual tension is caused by too much estrogen or problems with progesterone, but this is a discussion of ideas rather than results from a new study.

Early or limited evidence This is a review discussing women in general who experience emotional and physical changes during the menstrual cycle.

What they did

Review of existing research and theories about emotional and physical changes during the menstrual cycle and their possible causes.

What they found

Previous researchers proposed that premenstrual tension is caused either by too much estrogen that the body cannot get rid of, or by problems with progesterone production combined with too much estrogen. One prior paper showed that giving progesterone to women in the first part of the cycle changed their menstrual rhythm in ways similar to what happens in baboons.

What it means for you

The paper discusses several possible explanations for why some women experience premenstrual tension and mentions progesterone as a potential treatment. The main limitation is that this reviews other people's ideas and does not describe new research findings.

About the study

Original title
The Nature of the Subjective Reactions Evoked in Women by Progesterone with Special Reference to the Problem of Premenstrual Tension1
Authors
J Gillman
Journal
The Journal of Clinical Endocrinology & Metabolism
Year
1942
Study design
Study
What was tested
Progesterone (discussed as a potential treatment, not tested in this paper).

Topics