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Case-control study, 1988

Do women with PMS have vitamin or mineral deficiencies?

No. The study found no difference in vitamin and mineral levels between women with PMS and healthy women, so deficiencies probably do not cause PMS.

Moderate study design 38 women with PMS and 23 control women

What they did

Researchers measured blood levels of magnesium, zinc, vitamin A, vitamin E, and B vitamins in 38 women with PMS and 23 healthy women. They collected blood samples at two times: during the premenstrual phase and during the early part of the cycle.

What they found

There was no evidence that women with PMS had lower levels of any of the vitamins and minerals tested compared to healthy women.

What it means for you

Nutritional deficiencies are probably not the main cause of PMS. However, this is a relatively small study, so it does not completely rule out that nutritional supplements might help some women.

38

women with PMS

23

control women

5

nutrients measured

About the study

Original title
Vitamin and trace element status in premenstrual syndrome
Authors
Mira M, Stewart PM, Abraham SF
Journal
The American journal of clinical nutrition
Year
1988
Study design
Case-control study
Participants
38
What was tested
none

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