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Study, 2008

Is YAZ birth control safe and does it help PMDD?

YAZ is a birth control pill approved to prevent pregnancy, treat PMDD, and treat moderate acne. Large studies found it is safe with no increased risk of serious blood complications compared to other birth control pills.

Moderate study design Women using birth control, particularly those with PMDD or moderate acne

What they did

Describes YAZ, a birth control pill containing drospirenone 3 mg and ethinyl estradiol 20 micrograms, taken for 24 days followed by 4 days without hormones. Reports that two large studies evaluated its safety.

What they found

YAZ provides effective contraception and has a good safety profile. Large studies found no increased risk of high potassium levels or blood clots compared to other birth control pills. YAZ is approved for three uses: contraception, treatment of PMDD in women who want birth control, and treatment of moderate acne in women age 14 and older.

What it means for you

Women with PMDD who need birth control may be able to use YAZ, which could reduce both pregnancy risk and PMDD symptoms. Women with moderate acne who want contraception can also try YAZ. The pill has been studied in large groups and found to be safe. One limitation is the abstract does not report how much YAZ actually reduces PMDD symptoms, only that it is approved for this use.

3 mg

Drospirenone dose in YAZ

20 micrograms

Ethinyl estradiol dose in YAZ

24/4

Days of active pills followed by hormone-free days

About the study

Original title
YAZ and the novel progestin drospirenone
Authors
Mishell DR Jr
Journal
The Journal of reproductive medicine
Year
2008
Study design
Study
What was tested
YAZ birth control pill (drospirenone 3 mg with ethinyl estradiol 20 micrograms, 24 days active followed by 4 days off)

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