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Randomised trial, 2008

Does Chinese herbal medicine reduce PMS symptoms?

Yes. Chinese herbal medicine significantly reduced PMS symptoms (p < 0.001) with no adverse effects reported. Both groups received herbs and placebo in sequence, making the study design complex.

Moderate study design 61 Australian women with PMS

What they did

This was a controlled trial with 61 Australian women with PMS. Women were assigned to different groups based on traditional Chinese medicine patterns. Each group received both Chinese herbal medicine and placebo, given one after the other over a 3-month period. Symptoms were assessed at baseline and at the end of each treatment period.

What they found

Highly significant symptom reductions (p < 0.001) were found between baseline and the end of the third herbal treatment month in almost all assessments in both groups. Perceived stress showed significant improvement (p < 0.05) only in the group that received herbs first. No adverse effects were reported by any participant.

What it means for you

Chinese herbal medicine appears to reduce PMS symptoms significantly with no side effects. However, the complex design (sequential herbs and placebo) makes results harder to interpret. Strengths include no side effects and significant reductions. Limitations are the small sample (61 women), Australian population, and sequential design.

61

Australian women with PMS

3 months

study duration

p < 0.001

significance of symptom reduction

About the study

Original title
A controlled trial of Chinese herbal medicine for premenstrual syndrome
Authors
Chou PB, Morse CA, Xu H
Journal
Journal of psychosomatic obstetrics and gynaecology
Year
2008
Study design
Randomised trial
What was tested
Chinese herbal medicine based on traditional Chinese medicine patterns, given sequentially with placebo over 3 months
Open access
Yes
Original abstract

Premenstrual syndrome (PMS) is a common disorder troubling many women during their reproductive years. The Chinese have been using herbal medicines to treat menstrual cycle related symptoms for centuries. The present study examined the effectiveness of Chinese herbal medicine for the treatment of PMS among Australian women within the theoretical framework of traditional Chinese medicine (TCM). Sixty-one women were assigned randomly into two groups within different TCM patterns. Herbal medicine and placebo were provided sequentially for a period of three months. There were significant differences (p 0.05). There were highly significant reductions (p < 0.001) between baseline and the end of the third herbal treatment month in all assessments in both groups except that a significant result (p < 0.05) was recorded on perceived stress only in the herbs-first group. No adverse effects were reported by any participant. The results support the hypothesis that the symptoms occurrence and severity of PMS can be effectively reduced by the use of Chinese herbal medicine.

Reproduced under public-domain.

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