Skip to content

Survey study, 2009

Does brain activity change across the menstrual cycle?

Yes, brain activity in the prefrontal cortex shifts between different phases, with different sides of the brain being more active at different times. This is based on a small study.

Early or limited evidence 14 healthy women

What they did

Measured brain activity in 14 healthy women at different menstrual phases using magnetoencephalography while they looked at fearful faces. They measured brain responses in two time windows.

What they found

Brain activity showed different patterns across menstrual phases. The right side of the brain was more active during the periovulatory phase, while the left side became more active during the menstrual phase. In the menstrual phase, anxiety scores were associated with left prefrontal cortex activation.

What it means for you

The brain's emotional processing may change across the menstrual cycle. This is a very small study measuring brain waves in a laboratory, not everyday mood or behaviour.

14

women studied

200-300

milliseconds, first time window

300-450

milliseconds, second time window

About the study

Original title
Female menstrual phases modulate human prefrontal asymmetry: a magnetoencephalographic study
Authors
Hwang RJ, Wu CH, Chen LF et al.
Journal
Hormones and behavior
Year
2009
Study design
Survey study

Topics