Survey study, 2021
Can barley and chrysanthemum extract reduce PMS symptoms?
In laboratory tests and mice, this extract reduced prolactin and inflammation markers, which could help PMS, but human studies have not been done. We cannot say yet whether it works in women.
What they did
Laboratory and animal study. Researchers tested barley extract, chrysanthemum extract, and their mixture (Lomens-P0) in cells and in mice with high prolactin levels. They measured prolactin secretion, inflammation markers, and hormone levels.
What they found
Both extracts reduced prolactin secretion and inflammatory markers (IL-1β, IL-6, TNF-α, iNOS, COX-2) in laboratory cells (P < 0.01). In mice with high prolactin, Lomens-P0 suppressed prolactin secretion, normalized sex hormone balance, and significantly reduced inflammatory markers in uterine tissue. The active components were identified as tricin and chlorogenic acid.
What it means for you
This natural mixture might help prevent or treat PMS by lowering prolactin and inflammation. However, these are only laboratory and animal findings. No human studies are presented. We do not know if the extract works in women or at what dose.
P < 0.01
reduction in inflammatory markers in lab cells
About the study
- Original title
- Lomens-P0 (mixed extracts of Hordeum vulgare and Chrysanthemum zawadskii ) regulate the expression of factors affecting premenstrual syndrome symptoms
- Authors
- Lee YS, Jeon H, Her YM et al.
- Journal
- Nutrition research and practice
- Year
- 2021
- Study design
- Survey study
- What was tested
- Lomens-P0 extract (mixture of barley and chrysanthemum)
- Open access
- Yes
- Read the paper
- doi.org/10.4162/nrp.2021.15.6.715
Topics
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