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Cohort study, 2017

Which PMS symptoms best predict that PMS will interfere with work, relationships, and activities?

Psychological and emotional symptoms are the strongest predictors of how much PMS interferes with daily life. Having at least four cyclical symptoms best predicts significant impairment.

Moderate study design 267 women undergoing prospective assessment for PMDD in a research setting

What they did

267 women undergoing assessment for PMDD completed daily symptom diaries for 1 to 4 menstrual cycles. Researchers analyzed which specific symptoms predicted impairment in work, leisure, and relationships using statistical modeling.

What they found

Psychological symptoms (like difficulty concentrating, social withdrawal) were the strongest predictors of impairment. Emotional symptoms like sadness or mood swings predicted impairment but only before accounting for psychological symptoms. Four or more symptoms in the second half of the cycle optimally predicted clinically significant impairment. The five core diagnostic symptoms did not predict impairment better than having four.

What it means for you

If you have PMS, psychological symptoms like trouble focusing and withdrawing from others may matter more than mood symptoms alone for how much the condition disrupts your life. This suggests the current diagnostic threshold of five symptoms may be too high. Main limitation: this was a research setting and may not reflect all people with PMS.

267

Number of women studied

563

Total menstrual cycles analyzed

4

Optimal number of premenstrual symptoms predicting significant impairment

About the study

Original title
Predictors of premenstrual impairment among women undergoing prospective assessment for premenstrual dysphoric disorder: a cycle-level analysis
Authors
Schmalenberger KM, Eisenlohr-Moul TA, Surana P et al.
Journal
Psychological medicine
Year
2017
Study design
Cohort study
Participants
267
What was tested
None; this was an observational study
Open access
Yes

Topics