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Review, 2010

What is PMDD and how can it be treated?

PMDD is a severe set of mood and physical symptoms linked to estrogen that appear during the luteal phase and disappear within one week after menstruation. Treatment with SSRIs (antidepressants) shows promise but works best as part of a multidisciplinary approach.

Early or limited evidence Not a primary study; review of existing research

What they did

This is a review of existing research on PMDD, its diagnostic criteria, relationship to mood disorders, and treatment options including SSRIs.

What they found

PMDD appears as subjectively unpleasant mental and physical symptoms during the luteal phase and disappears by one week after menstruation. It is now classified as a separate psychiatric diagnosis in DSM-IV-TR but is not specifically included in ICD-10. SSRIs are discussed as an effective treatment option.

What it means for you

PMDD is recognized as a serious menstrual cycle-related condition distinct from regular PMS, but diagnostic criteria differ between classification systems worldwide. This inconsistency affects how the condition is recognized and treated globally. Treatment requires a multidisciplinary approach beyond antidepressants alone.

3

Classification systems discussed

About the study

Original title
Premenstrual dysphoric disorder--review of actual findings about mental disorders related to menstrual cycle and possibilities of their therapy
Authors
Zukov I, Ptácek R, Raboch J et al.
Journal
Prague medical report
Year
2010
Study design
Review
What was tested
Treatment options reviewed, particularly SSRIs

Topics