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Study, 2008

What causes severe PMS and how is it treated?

Severe PMS is caused by the body's reaction to normal hormone changes during the menstrual cycle. It is treatable with hormonal methods or antidepressants.

Early or limited evidence Review of severe PMS and PMDD generally; not a specific study population

What they did

Reviewed what is known about severe PMS and PMDD, their causes, and their treatments.

What they found

About 5-8% of women have severe PMS, and most of these also have PMDD. Mood symptoms like irritability, mood swings, and depression are usually the most distressing, though physical symptoms like breast tenderness and bloating can also be very problematic. Treatments that stop ovulation (such as birth control pills, hormone patches, or GnRH medications) work well. Antidepressants that affect serotonin, taken throughout the cycle or just during the luteal phase, also work well.

What it means for you

Severe PMS is a real medical condition affecting a small percentage of women. It is treatable using hormonal methods or antidepressants. This review summarizes knowledge from 2008, so newer treatments may have emerged since then.

5-8%

Women with severe PMS

About the study

Original title
Premenstrual syndrome
Authors
Yonkers KA, O'Brien PM, Eriksson E
Journal
Lancet (London, England)
Year
2008
Study design
Study
Open access
Yes

Topics