Review, 2024
How does the traditional Chinese medicine Chaihu Shugan Powder work to treat PMS?
This review identifies that the formula may work through 17 signaling pathways and 75 molecular targets to reduce PMS symptoms. However, the mechanism has only been studied theoretically and no clinical trials have tested it yet.
What they did
Literature review analyzing the traditional Chinese medicine formula Chaihu Shugan Powder using network pharmacology. Researchers reviewed literature on ingredients and mechanisms, then used computer analysis to identify molecular targets and pathways.
What they found
The formula contains 7 herbal ingredients with multiple active compounds. Network pharmacology identified 75 common molecular targets relevant to PMS treatment, concentrated in 17 signaling pathways. The formula has been traditionally used for liver detoxification and depression relief and is one of the most widely used formulas for treating PMS.
What it means for you
The formula may work through multiple molecular pathways. However, this was only a literature and computer analysis. No laboratory, animal, or human experiments were conducted. Clinical trials are needed to know if it actually works and which ingredients are responsible.
7
herbal ingredients in the formula
75
molecular targets identified
17
signaling pathways identified
About the study
- Original title
- Research progress of traditional Chinese medicine compound "Chaihu Shugan Powder" in the treatment of premenstrual syndrome
- Authors
- Chu Z, Gao M, Wang J et al.
- Journal
- Medicine
- Year
- 2024
- Study design
- Review
- What was tested
- Chaihu Shugan Powder (traditional Chinese medicine formula) - theoretical analysis only
- Open access
- Yes
- Read the paper
- doi.org/10.1097/md.0000000000038351
Topics
Related studies
Systematic review, 2026
Which traditional Chinese medicine treatments work best for PMS?
Randomised trial, 2025
Do essential oils reduce PMS symptoms?
Randomised trial, 2025
Which is more effective for PMS - Vitagnus, soy, or both together?
Randomised trial, 2025
Does the PMSoff supplement help PMS and PMDD symptoms?
Randomised trial, 2024
Is Jiawei Xiaoyao pill effective and safe for treating premenstrual syndrome?
Randomised trial, 2024
Is Ganyushu Granule effective and safe for premenstrual syndrome?