Review, 1999
Can different progestin hormones help treat various women's health problems before menopause?
This is a general overview article, not a new study. It explains that different progestins may suit different conditions, but it gives no trial results to prove any specific benefit.
What they did
This is a review article, not a new experiment with patients. The author summarises existing medical knowledge about progestins (hormones related to progesterone) and how doctors might choose between them based on their different properties.
What they found
The review explains that progestins have varied effects, described as androgenic, antiandrogenic, estrogenic, antiestrogenic, glucocorticoid and others. It says these properties can be matched to conditions including bleeding disorders, benign breast disease, endometrial hyperplasia, endometriosis, contraception, androgenization, and gynecological cancers. No specific numbers, doses or trial results are given in the abstract.
What it means for you
This paper is written to guide doctors' thinking, not a scientific study you can draw firm conclusions from. It does not test or prove that progestins help PMS or PMDD specifically, and there is no patient data, sample size or control group.
About the study
- Original title
- Role of progestins in the premenopausal climacteric
- Authors
- Schindler AE
- Journal
- Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology
- Year
- 1999
- Study design
- Review
- What was tested
- No specific treatment was tested; the review discusses progestins as a drug class in general.
- Read the paper
- https://pubmed.ncbi.nlm.nih.gov/10862267/
Topics
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