Non-randomised trial, 1993
Do women with PMDD react more strongly to lactate challenge?
Yes. 58% of women with PMDD had panic responses to sodium lactate injection, compared to 0% of control women.
What they did
13 women with PMDD and 7 control women received sodium lactate infusions. Researchers measured whether they had panic responses and the severity of panic symptoms.
What they found
7 of 13 women with PMDD (58%) had panic responses, compared to 0 of 7 control women (0%). Non-panicking women with PMDD also had higher panic scores than controls.
What it means for you
Women with PMDD may respond differently to lactate, but the clinical significance is unclear. This was a small, non-randomized study.
7 of 13 (58%)
PMDD women with panic response
0 of 7 (0%)
Control women with panic response
About the study
- Original title
- Sodium lactate infusion in late luteal phase dysphoric disorder
- Authors
- Sandberg D, Endicott J, Harrison W et al.
- Journal
- Psychiatry research
- Year
- 1993
- Study design
- Non-randomised trial
- Participants
- 13
- What was tested
- Sodium lactate infusion
- Read the paper
- doi.org/10.1016/0165-1781(93)90010-e
Topics
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