Skip to content

Case-control study, 2026

Does vitamin D help PMS symptoms?

Evidence from clinical trials suggests taking vitamin D supplements or eating foods rich in vitamin D can reduce PMS symptoms. Low vitamin D during the menstrual cycle may make PMS worse.

Moderate study design Women of reproductive age; review of clinical trials and observational studies

What they did

Literature review searching medical databases for clinical trials, case-control studies and other research on vitamin D and PMS.

What they found

PMS affects millions of women during the luteal phase of their cycle and has multiple causes including hormones, brain chemicals, inflammation and genetics. Clinical trials show vitamin D supplementation or a diet rich in vitamin D can reduce PMS symptoms, possibly by regulating hormones, affecting brain chemistry and reducing inflammation. Low calcium and vitamin D levels during the luteal phase may worsen PMS. Vitamin D supplements are affordable, safe and easy to get. However, current research has limitations from small study sizes and different study methods.

What it means for you

Vitamin D supplementation is a safe, affordable option for managing PMS, especially if levels are low. It may work through multiple pathways in the body. However, current research is limited by small studies and inconsistent methods, so larger well-designed studies are needed to confirm benefits and guide dosing. Main limits: small sample sizes and varied study designs.

About the study

Original title
Vitamin D deficiency and premenstrual syndrome (PMS) Literature Review
Authors
Dominika Cholewa, Dominik Jaklik, Natalia Guzik et al.
Journal
Quality in Sport
Year
2026
Study design
Case-control study
What was tested
Vitamin D supplementation or dietary vitamin D
Open access
Yes

Topics