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Study, 2010

Which PMDD medication is most cost-effective?

This analysis suggests the birth control pill DRSP/EE may be the most cost-effective option for PMDD treatment, though fluoxetine could be cost-effective depending on how much someone is willing to spend.

Early or limited evidence This is an economic analysis based on published studies and cost data, not a direct study of women

What they did

Researchers used a mathematical model to compare costs and treatment success of four FDA-approved PMDD medications: fluoxetine, sertraline, paroxetine, and DRSP/EE. They looked at medication costs, doctor visit costs, and how many women improved at 6 months based on published studies.

What they found

Starting with DRSP/EE was more cost-effective than sertraline or paroxetine. Compared to fluoxetine, DRSP/EE was less expensive overall, though fluoxetine could be the better value depending on someone's budget for treatment success.

What it means for you

This analysis used cost estimates from 2007 and treatment success rates from published studies, not new testing of these medications. Real-world costs and how well they work today might differ. This can help inform treatment choices when cost matters, but women respond differently.

4

medications compared

6 months

time measured for treatment success

About the study

Original title
Cost-effectiveness analysis of treatments for premenstrual dysphoric disorder
Authors
Rendas-Baum R, Yang M, Gricar J et al.
Journal
Applied health economics and health policy
Year
2010
Study design
Study

Topics