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Review, 2010

What is the recommended way to diagnose and treat PMDD?

PMDD affects 3-5% of women and causes severe symptoms. Selective serotonin reuptake inhibitors (SSRIs, a type of antidepressant) taken during the luteal phase (the two weeks before menstruation) are considered first-line therapy.

Strong study design Women with PMDD

What they did

This is a review article presenting a diagnostic algorithm and treatment approach for PMDD.

What they found

PMDD affects 3-5% of women and causes severe depression and anxiety symptoms that impair social and work functioning. The symptoms are linked to serotonin dysregulation. SSRIs taken only during the symptomatic luteal phase are first-line therapy.

What it means for you

PMDD has a clear recommended treatment pathway using antidepressants taken intermittently. This is a review, not original research.

3-5%

women with PMDD

About the study

Original title
[Diagnostic and therapeutic algorithm for the treatment of premenstrual dysphoric disorder]
Authors
Strkalj Ivezić S, Kusan Jukić M, Tikvica A et al.
Journal
Acta medica Croatica : casopis Hravatske akademije medicinskih znanosti
Year
2010
Study design
Review
What was tested
SSRI antidepressants (taken during luteal phase)

Topics